General Parvo (voiced by Jim Cummings) is the main antagonist of the series. He is out to destroy Professor Shepherd and conquer the world. He has a permanent cough. It was revealed later in the series that General Parvo was at one time a Cat before being transformed into a "Feline Sapien", which resemble humans a great deal more than Shepherd's Cano-sapiens. He shares a very similar appearance to wrestler Hulk Hogan. The name Parvo derives from a canine disease which often kills puppies.